Trifluoroacetic acid → HCID 178514771, compound

HRID 1390895Notes

Reaction equation

HRID 1390895 reaction equation
C([O:5][C:6]([C:8]1[N:13]2[C:14](=[O:28])[CH:15]([NH:16][C:17](=[O:27])[CH2:18][S:19]([CH2:22][C:23]([F:26])([F:25])[F:24])(=[O:21])=[O:20])[C@H:12]2[S:11][CH2:10][C:9]=1[CH:29]([S:36][C:37]1[NH:41][N:40]=[N:39][N:38]=1)[CH2:30][CH2:31][S:32](=[O:35])(=[O:34])[NH2:33])=[O:7])(C)(C)C.FC(F)(F)C(O)=O>C(#N)C>[F:26][C:23]([F:24])([F:25])[CH2:22][S:19]([CH2:18][C:17]([NH:16][CH:15]1[C:14](=[O:28])[N:13]2[C:8]([C:6]([OH:7])=[O:5])=[C:9]([CH:29]([S:36][C:37]3[NH:41][N:40]=[N:39][N:38]=3)[CH2:30][CH2:31][S:32](=[O:34])(=[O:35])[NH2:33])[CH2:10][S:11][C@H:12]12)=[O:27])(=[O:21])=[O:20]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 1784507027-(2,2,2-Trifluoroethylsulfonylacetamido)-3-[1-(2-sulfamoylethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acid t-butyl ester

Product 1

HCID 178514771HCID 178514771, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The ester is dissolved in acetonitrile and trifluoroacetic acid is added. The solution is stirred for three hours, then evaporated to dryness to give the title compound.

Workup

  1. customevaporated to dryness

Sources & evidence

ORD record
ord-0c8dce7650d04792a154485d06645d49
Source dataset
uspto-grants-1979_02
Patent number
US04140694

Reaction notes

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