Thionyl Chloride → HCID 20306079, compound

HRID 1390927Notes

Reaction equation

HRID 1390927 reaction equation
[Cl:1][C:2]1[C:13]([C:14](=[O:20])[C:15]2[S:19][CH:18]=[CH:17][CH:16]=2)=[CH:12][C:5]2[CH2:6][CH:7]([C:9](O)=[O:10])[O:8][C:4]=2[C:3]=1[Cl:21].S(Cl)([Cl:24])=O>C1C=CC=CC=1>[Cl:1][C:2]1[C:13]([C:14](=[O:20])[C:15]2[S:19][CH:18]=[CH:17][CH:16]=2)=[CH:12][C:5]2[CH2:6][CH:7]([C:9]([Cl:24])=[O:10])[O:8][C:4]=2[C:3]=1[Cl:21]

Participants

4

Reactant 2

HCID 24386Thionyl Chloride2×HCID 12747881HCID 12747881, compound

Product 1

HCID 20306079HCID 20306079, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

6,7-Dichloro-2,3-dihydro-5-(2-thenoyl)-2-benzofuran carboxylic acid (3.4 g.; 0.01M.) is combined with 2 ml. thionyl chloride and 50 ml. benzene. After 2 hours at reflux the excess thionyl chloride and benzene are removed by distillation at 20 mmHg to give 6,7-dichloro-2,3-dihydro-5-(2-thenoyl)-2-benzofuran carboxylic acid chloride as a yellow oil.

Workup

  1. customare removed by distillation at 20 mmHg

Sources & evidence

ORD record
ord-89fd6a62f7a8442998d5267dcec6caf0
Source dataset
uspto-grants-1979_02
Patent number
US04140776

Reaction notes

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