Hydrochloric Acid → HCID 21331930, compound

HRID 1390929Notes

Reaction equation

HRID 1390929 reaction equation
[CH:1]([NH:4][CH2:5][CH:6]([CH2:13][O:14][C:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:18]=[CH:17][CH:16]=1)[N:7]1[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1)(C)[CH3:2].Cl>>[CH2:1]([NH:4][CH2:5][CH:6]([CH2:13][O:14][C:15]1[C:24]2[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=2)[CH:18]=[CH:17][CH:16]=1)[N:7]1[CH2:12][CH2:11][CH2:10][CH2:9][CH2:8]1)[CH3:2]

Participants

3

Reactant 2

HCID 313Hydrochloric Acid2×HCID 21331941HCID 21331941, compound

Product 1

HCID 21331930HCID 21331930, compound

Procedure

N-isopropyl-β-[(1-naphthyloxy)methyl]-1-piperidineethanamine mmr (CDCl3) δ 1.12 (3, 9H), 1.5 (m, 6H), 2.08 (s, 1H), 2.85 (m, 7H), 4.25 (m, 2) and 6.8 - 8.4 (m, 7H), the corresponding hydrochloric acid addition salt (hydrochloride) of the latter compound has mp 182-184° C., after recrystallization from ethyl acetate-methanol-diethyl ether,

Workup

  1. customafter recrystallization from ethyl acetate-methanol-diethyl ether

Sources & evidence

ORD record
ord-317c744fd32b4357b5de74b363e58912
Source dataset
uspto-grants-1979_02
Patent number
US04140779

Reaction notes

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