1-(3,5-Dibromophenyl)-4-(p-nitrobenzyl)piperazine → HCID 21331900, compound

HRID 1391012Notes

Reaction equation

HRID 1391012 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][C:16]3[CH:21]=[CH:20][C:19]([N+:22]([O-])=O)=[CH:18][CH:17]=3)[CH2:11][CH2:10]2)[CH:5]=[C:6]([Br:8])[CH:7]=1>[Cl-].[Cl-].[Cl-].[Ti+3]>[Br:1][C:2]1[CH:3]=[C:4]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][C:16]3[CH:21]=[CH:20][C:19]([NH2:22])=[CH:18][CH:17]=3)[CH2:11][CH2:10]2)[CH:5]=[C:6]([Br:8])[CH:7]=1

Participants

3

Reactant 1

HCID 213318281-(3,5-Dibromophenyl)-4-(p-nitrobenzyl)piperazine

Product 1

HCID 21331900HCID 21331900, compound

Reagents, catalysts & solvents 1

HCID 10313229titanium(III) trichlorideCatalyst

Procedure

In the manner given in Example 1B, 1-(3,5-dibromophenyl)-4-(p-nitrobenzyl)piperazine is reduced with aqueous titanium trichloride to give 1-(3,5-dibromophenyl)-4-[(4-aminophenyl)methyl]piperazine.

Sources & evidence

ORD record
ord-03ab66ecd3fe45f6be018c43bd686299
Source dataset
uspto-grants-1979_02
Patent number
US04140775

Reaction notes

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