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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1391012Generated: October 26, 2026

1-(3,5-Dibromophenyl)-4-(p-nitrobenzyl)piperazine → 1-(3,5-Dibromophenyl)-4-[(4-aminophenyl)methyl]piperazine

https://huagongshe.com/reaction/1391012

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3,5-Dibromophenyl)-4-(p-nitrobenzyl)piperazineHCID 21331828—
Catalysttitanium(III) trichlorideHCID 10313229—
Product1-(3,5-Dibromophenyl)-4-[(4-aminophenyl)methyl]piperazineHCID 21331900—

Reaction Steps

In the manner given in Example 1B, 1-(3,5-dibromophenyl)-4-(p-nitrobenzyl)piperazine is reduced with aqueous titanium trichloride to give 1-(3,5-dibromophenyl)-4-[(4-aminophenyl)methyl]piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04140775
Source datasetuspto-grants-1979_02
ORD IDord-03ab66ecd3fe45f6be018c43bd686299
Source noteuspto-grants-1979_02