Ethyl isothiocyanate → HCID 178465508, compound

HRID 1391210Notes

Reaction equation

HRID 1391210 reaction equation
[NH:1]1[C:9]2[CH2:8][CH2:7][NH:6][CH2:5][C:4]=2[N:3]=[CH:2]1.[CH2:10]([N:12]=[C:13]=[S:14])[CH3:11]>C(#N)C>[CH2:10]([NH:12][C:13]([N:6]1[CH2:7][CH2:8][C:9]2[NH:1][CH:2]=[N:3][C:4]=2[CH2:5]1)=[S:14])[CH3:11]

Participants

4

Reactant 2

HCID 10966Ethyl isothiocyanateHCID 178420865HCID 178420865, compound

Product 1

HCID 178465508HCID 178465508, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A solution of 1.85 g of 4,5,6,7-tetrahydro-imidazo-[4,5-c]-pyridine and 2 g of ethyl isothiocyanate in 15 ml of acetonitrile are refluxed for 7 h. The solution is cooled and filtered: 2.5 g of 5-[N-ethyl-thiocarbamoyl]-4,5,6,7-tetrahydro-imidazo-[4,5-c]-pyridine, m.p. 185°, are collected.

Workup

  1. temperatureThe solution is cooled
  2. filtrationfiltered
  3. custom2.5 g of 5-[N-ethyl-thiocarbamoyl]-4,5,6,7-tetrahydro-imidazo-[4,5-c]-pyridine, m.p. 185°, are collected

Sources & evidence

ORD record
ord-a6e00b8e4b894491b68e41761719e065
Source dataset
uspto-grants-1979_02
Patent number
US04141899

Reaction notes

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