HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl isothiocyanate → HCID 21330758, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl isothiocyanate | HCID 11167 | — |
| Reactant | 4-Phenyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine | HCID 256467 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 21330758 | HCID 21330758 | — |
Reaction Steps
A solution of 3.5 g of 4-phenyl-4,5,6,7-tetrahydro-imidazo-[4,5-c]-pyridine (Farmaco, Ed. Sci., 1967, 22, 821) and 3.5 g of methyl isothiocyanate in 55 ml of dioxane is refluxed for 4 h. The solution is cooled and filtered: 3.6 g of 4-phenyl-5-(N-methyl-thiocarbamoyl)-4,5,6,7-tetrahydroimidazo-[4,5-c]-pyridine, m.p. 228°, are collected.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04141899 |
| Source dataset | uspto-grants-1979_02 |
| ORD ID | ord-3d4a4a3df46d499d817a2c46dcc94b5c |
| Source note | uspto-grants-1979_02 |