Red-Al → HCID 70608796, compound

HRID 1391249Notes

Reaction equation

HRID 1391249 reaction equation
O=[C:2]1[C@@H:8]2[CH2:9][CH2:10][CH2:11][C@@:7]2([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH3:19])[CH:13]=2)[CH2:6][CH2:5][CH2:4][N:3]1[CH3:20].COCCO[AlH2-]OCCOC.[Na+]>C1C=CC=CC=1>[CH3:20][N:3]1[CH2:4][CH2:5][CH2:6][C@:7]2([C:12]3[CH:17]=[CH:16][CH:15]=[C:14]([O:18][CH3:19])[CH:13]=3)[CH2:11][CH2:10][CH2:9][C@H:8]2[CH2:2]1

Participants

4

Reactant 2

HCID 16684438Red-AlHCID 70608295HCID 70608295, compound

Product 1

HCID 70608796HCID 70608796, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Following the procedure set out in Example 7, dl-trans-1-oxo-2-methyl-5a-(3-methoxyphenyl)-decahydrocyclopent[c]azepine was reacted with Red-al® in benzene to provide dl-trans-2-methyl-5a-(3-methoxyphenyl)-decahydrocyclopent[c]azepine. B.P. 130°-140° C. at 0.05 torr.

Sources & evidence

ORD record
ord-588b1d4ed0d24637b54167e56dd29c4e
Source dataset
uspto-grants-1979_02
Patent number
US04141893

Reaction notes

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