Cyclopropanecarboxylic acid → Cyclopropanecarboxylic acid anhydride

HRID 1391283Notes

Reaction equation

HRID 1391283 reaction equation
[CH:1]1([C:4]([OH:6])=[O:5])[CH2:3][CH2:2]1.[CH:7]1([C:10](Cl)=[O:11])[CH2:9][CH2:8]1>>[CH:1]1([C:4]([O:6][C:10]([CH:7]2[CH2:9][CH2:8]2)=[O:11])=[O:5])[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 15655Cyclopropanecarboxylic acidHCID 77637Cyclopropanecarbonyl chloride

Product 1

HCID 297009Cyclopropanecarboxylic acid anhydride

Procedure

This was prepared from cyclopropanecarboxylic acid (Aldrich) and cyclopropanecarboxylic acid chloride (Aldrich) by the method given (Example IV) for the preparation of the cyclobutyl analogue and purified by vacuum distillation; bp 95°-100° C. at 6 torr (lit.: Castro and Dormoy, Bull. Soc. Chem. Fr. 8, 3034 (1971) bp 102°-104° C. at 8 torr); IR anhydride C=O stretch absorptions at 5.53 and 5.74μ.

Workup

  1. distillationpurified by vacuum distillation

Sources & evidence

ORD record
ord-a690a1f727504d85a62688187e3542e8
Source dataset
uspto-grants-1979_02
Patent number
US04141897

Reaction notes

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