Hydrochloric Acid → HCID 131711434, compound

Participants

Reaction Steps

10.6 grams (0.264 moles) of (±)-trans-1,3,4,4a,5,9b-hexahydro-5-phenyl-2H-pyrido[4,3-b]indole-2-butyric acid, ethyl ester, hydrochloride (the compound of Example 4) was suspended in 80 ml. of 6N hydrochloric acid and was refluxed for 20 minutes. Immediately upon cooling, a precipitate was obtained which was filtered and washed with a small quantity of water giving the title compound, m.p. 238.5°-240° C. (dec.).

Provenance & Evidence