HRID1391632

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID559410

3-(morpholinosulfonyl)aniline

C10H14N2O3S

结构：Cn1c(Nc2cc(C(C)(C)C)on2)nc2cc(Nc3ccnc(Cl)n3)ccc21

HCID91543477

未命名化合物

PRODUCTS

生成物

结构：Cn1c(Nc2cc(C(C)(C)C)on2)nc2cc(Nc3ccnc(Nc4cccc(S(=O)(=O)N5CCOCC5)c4)n3)ccc21

HCID44526736

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following the procedure of Example I with N2-(5-tert-Butyl-isoxazol-3-yl)-N5-(2-chloro-pyrimidin-4-yl)-1-methyl-1H benzoimidazole-2,5-diamine (35 mg, 0.09 mmol) and 3-(Morpholine-4-sulfonyl)-phenylamine (23 mg, 0.10 mmol) to afford an off white solid (32 mg, 005. mmol). MS (ESI) m/z=605 [M+H]+.

WORKUP

后处理

customto afford an off white solid (32 mg, 005. mmol)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-adc4ebe4b72f46678a1f8465137ad006
来源数据集: uspto-grants-2008_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07338959B2
来源说明: uspto-grants-2008_03

反应 SMILES

[C:1]([C:5]1[O:9][N:8]=[C:7]([NH:10][C:11]2[N:15]([CH3:16])[C:14]3[CH:17]=[CH:18][C:19]([NH:21][C:22]4[CH:27]=[CH:26][N:25]=[C:24](Cl)[N:23]=4)=[CH:20][C:13]=3[N:12]=2)[CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[N:29]1([S:35]([C:38]2[CH:39]=[C:40]([NH2:44])[CH:41]=[CH:42][CH:43]=2)(=[O:37])=[O:36])[CH2:34][CH2:33][O:32][CH2:31][CH2:30]1>>[C:1]([C:5]1[O:9][N:8]=[C:7]([NH:10][C:11]2[N:15]([CH3:16])[C:14]3[CH:17]=[CH:18][C:19]([NH:21][C:22]4[CH:27]=[CH:26][N:25]=[C:24]([NH:44][C:40]5[CH:41]=[CH:42][CH:43]=[C:38]([S:35]([N:29]6[CH2:34][CH2:33][O:32][CH2:31][CH2:30]6)(=[O:37])=[O:36])[CH:39]=5)[N:23]=4)=[CH:20][C:13]=3[N:12]=2)[CH:6]=1)([CH3:4])([CH3:3])[CH3:2]