3-(Morpholine-4-sulfonyl)aniline → 2-N-(5-tert-butyl-1,2-oxazol-3-yl)-1-methyl-5-N-[2-(3-morpholin-4-ylsulfonylanilino)pyrimidin-4-yl]benzimidazole-2,5-diamine

Participants

Reaction Steps

The title compound was prepared following the procedure of Example I with N2-(5-tert-Butyl-isoxazol-3-yl)-N5-(2-chloro-pyrimidin-4-yl)-1-methyl-1H benzoimidazole-2,5-diamine (35 mg, 0.09 mmol) and 3-(Morpholine-4-sulfonyl)-phenylamine (23 mg, 0.10 mmol) to afford an off white solid (32 mg, 005. mmol). MS (ESI) m/z=605 [M+H]+.

Provenance & Evidence