Methyl levulinate → Levulinic Acid

HRID 1391854Notes

Reaction equation

HRID 1391854 reaction equation
C[O:2][C:3](=[O:10])[CH2:4][CH2:5][C:6]([CH2:8]Cl)=[O:7].[CH2:11]([O:13][C:14](=[O:22])[CH2:15][CH:16](Cl)[C:17]([CH2:19]Cl)=[O:18])C.COC(=O)CCC(C)=O>>[C:3]([OH:10])(=[O:2])[CH2:4][CH2:5][C:6]([CH3:8])=[O:7].[CH3:11][O:13][C:14](=[O:22])[CH2:15][CH2:16][C:17]([CH3:19])=[O:18]

Participants

5

Reactant 3

HCID 69354Methyl levulinateHCID 11789557Methyl 5-chloro-4-oxopentanoateHCID 15716073Ethyl 3,5-dichloro-4-oxopentanoate

Product 2

HCID 11579Levulinic AcidHCID 69354Methyl levulinate

Procedure

Preparation of 5-chlorolevulinic acid methyl ester from a mixture of 3-chloro-, 5-chloro-, 3,5-dichlorolevulinic acid ethyl ester and levulinic acid methyl ester consisting of the same product ratio, which is obtained by the bromination of both levulinic acid and levulinic acid methyl ester according to the Examples 1 and 2.

Sources & evidence

ORD record
ord-f9c5c017313a4f1f9985502401a0b1ef
Source dataset
uspto-grants-2008_03
Patent number
US07339073B2

Reaction notes

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