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HRID1392376

反应详情

EQUATION

反应方程式

HRID 1392376 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：Nc1nc(CC(=O)Nc2ccc(CCNC[C@H](O)c3ccccc3)cc2)cs1
HCID9865528

Mirabegron

C21H24N4O2S

PRODUCTS

生成物

1
结构：Cl.Cl.Nc1nc(CC(=O)Nc2ccc(CCNC[C@H](O)c3ccccc3)cc2)cs1
HCID86595764

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

20.0 g of (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]acetanilide was dissolved in 1,4-dioxane, to which was then added 8.41 mL of concentrated hydrochloric acid. A generated crystal was collected by filtration to obtain 25.0 g of (R)-2-(2-aminothiazol-4-yl)-4′-[2-[(2-hydroxy-2-phenylethyl)amino]ethyl]-acetanilide dihydrochloride.

WORKUP

后处理

  1. filtrationA generated crystal was collected by filtration