Benzene, 1-bromo-2-(trifluoromethyl)- → HCID 69311880, compound

Participants

Reaction Steps

In accordance with the same procedure as in Example 24, except that 4-[N-[1-[N-(benzyloxycarbonyl)amino]cyclohexanecarbonyl]amino]-1-(4-fluoro-2-aminophenyl)piperidin-3-ol hydrochloride was used instead of 4-[N-[1-[N-(benzofuran-2-ylcarbonyl)amino]cyclohexanecarbonyl]amino]-3-piperidinol hydrochloride and 1-bromo-2-trifluoromethylbenzene was used instead of 1-bromo-4-fluoro-2-trifluoromethylbenzene in Step 1 of Example 24, 228 mg of the titled compound was prepared.

Provenance & Evidence