Tert-Butylamine → HCID 178449860, compound

Participants

Reaction Steps

Omeprazole (1.0 g, 2.9 mmol) was dissolved in tert-butyl methyl ether (10 ml) at 60-70° C. Tert-butylamine (0.60 g, 8.1 mmol) was added and the mixture was then cooled to room temperature whereupon the product crystallised. The formed precipitate was filtered off and washed with in tert-butyl methyl ether. The title compound was obtained as a white solid.

Provenance & Evidence