Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | N-(2,6-Dichlorobenzoyl)-4-nitro-L-phenylalanine | HCID 58018322 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 58018321 | HCID 58018321 | — |
Reaction Steps
Isopropanol (130 mL), tetrahydrofuran (50 mL) and sulfuric acid (0.44 mL) were added to 4-nitro-N-(2,6-dichlorobenzoyl)-L-phenylalanine (2.95 g, 7.70 mmol) and stirred at 50° C. for 5 days. After removing the solvent under reduced pressure, the obtained solid material was washed with water and dried to obtain 3.28 g of a white solid material.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07345049B2 |
|---|
| Source dataset | uspto-grants-2008_03 |
|---|
| ORD ID | ord-7f0384011cc04bccb8a0f3eda6d020dd |
|---|
| Source note | uspto-grants-2008_03 |
|---|
