Trifluoroacetic acid → HCID 45095492, compound

HRID 1393085Notes

Reaction equation

HRID 1393085 reaction equation
[CH3:1][O:2][C:3](=[O:23])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([N:12](C(OC(C)(C)C)=O)[CH3:13])=[CH:8][C:7]=1[CH2:21][CH3:22].C(O)(C(F)(F)F)=O>>[CH3:1][O:2][C:3](=[O:23])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([NH:12][CH3:13])=[CH:8][C:7]=1[CH2:21][CH3:22]

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 69219069HCID 69219069, compound

Product 1

HCID 45095492HCID 45095492, compound

Procedure

Analogously, to example 1.4, [4-(tert-butoxycarbonyl-methyl-amino)-2-ethyl-phenoxy]-acetic acid methyl ester was deprotected with TFA to give (2-ethyl-4-methylamino-phenoxy)-acetic acid methyl ester as a light brown oil, MS: 224 (MH+).

Sources & evidence

ORD record
ord-0a54742fcf994d939c655049d0103e64
Source dataset
uspto-grants-2008_03
Patent number
US07345067B2

Reaction notes

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