Methyl iodide → HCID 69217710, compound

HRID 1393104Notes

Reaction equation

HRID 1393104 reaction equation
[CH2:1]([O:3][C:4](=[O:33])[CH2:5][O:6][C:7]1[C:12]([CH3:13])=[CH:11][C:10]([NH:14][CH2:15][C:16]2[O:20][C:19]([C:21]3[CH:26]=[CH:25][C:24]([C:27]([F:30])([F:29])[F:28])=[CH:23][CH:22]=3)=[N:18][C:17]=2[CH3:31])=[CH:9][C:8]=1[CH3:32])[CH3:2].CI.[CH2:36](I)C>>[CH2:1]([O:3][C:4](=[O:33])[CH2:5][O:6][C:7]1[C:12]([CH3:13])=[CH:11][C:10]([N:14]([CH3:36])[CH2:15][C:16]2[O:20][C:19]([C:21]3[CH:22]=[CH:23][C:24]([C:27]([F:28])([F:30])[F:29])=[CH:25][CH:26]=3)=[N:18][C:17]=2[CH3:31])=[CH:9][C:8]=1[CH3:32])[CH3:2]

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 6340IodoethaneHCID 69219047HCID 69219047, compound

Product 1

HCID 69217710HCID 69217710, compound

Procedure

The title compound was prepared in analogy to example 15.4 from the above prepared (2,6-dimethyl-4-{[4-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-5-ylmethyl]-amino}-phenoxy)-acetic acid ethyl ester, but using methyl iodide as electrophile instead of ethyl iodide, as off-white solid, MS: 477.5 (MH)+.

Sources & evidence

ORD record
ord-d058d4b0b7a044d082b1f05b690450a8
Source dataset
uspto-grants-2008_03
Patent number
US07345067B2

Reaction notes

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