P,P-Diphenylphosphinic azide → HCID 23033880, compound

HRID 1393360Notes

Reaction equation

HRID 1393360 reaction equation
COC[O:4][CH2:5][C:6]1[CH:7]=[CH:8][CH:9]=[C:10]2[C:15]=1[O:14][C:13]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[C:12](C(O)=O)[C:11]2=[O:25].C1(P([N:40]=[N+]=[N-])(C2C=CC=CC=2)=O)C=CC=CC=1.Cl.O1CCOCC1>C(O)(C)(C)C>[NH2:40][C:12]1[C:11](=[O:25])[C:10]2[C:15](=[C:6]([CH2:5][OH:4])[CH:7]=[CH:8][CH:9]=2)[O:14][C:13]=1[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

5

Reactant 3

HCID 199401P,P-Diphenylphosphinic azideHCID 204431481,4-Dioxane hydrochlorideHCID 23033922HCID 23033922, compound

Product 1

HCID 23033880HCID 23033880, compound

Reagents, catalysts & solvents 1

HCID 6386tert-ButanolSolvent

Procedure

8-Methoxymethoxymethylflavone-3-carboxylic acid was reacted with diphenylphosphoryl azide and then with t-butanol. The resultant product was hydrolyzed with aqueous hydrochloric acid-dioxane to give 3-aminoflavone-8-methanol.

Sources & evidence

ORD record
ord-c4360740764645a884ff489349d1e9de
Source dataset
uspto-grants-2008_03
Patent number
US07345068B2

Reaction notes

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