HCID 86598325, compound → HCID 69320224, compound

Participants

Reaction Steps

In a similar manner to Example 49-1), 3-[4-(4-hydroxyphenoxy)-phenoxy]-L-phenylalanine was synthesized by deprotecting by a conventional method from N-trifluoroacetyl-3-(4-hydroxyphenoxy)-L-phenylalanine ethyl ester via N-trifluoroacetyl-3-[4-(4-methoxyphenoxy)phenoxy]-L-phenylalanine ethyl ester. N-Trifluoroacetyl-3-[4-(4-methoxyphenoxy)phenoxy]-L-phenylalanine ethyl ester: m.p.: 67-71° C.; IR (Nujol): 3324, 1745, 1707, 1559, 1507, 1501 cm−1; APCI-MS m/z: 504 [M+H]+.

Provenance & Evidence