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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1393592Generated: October 26, 2026

4-Chlorobenzenesulfonyl chloride → 6-[[5-[[(4-Chlorophenyl)sulfonyl]amino]-1-(4-methoxyphenyl)-2-(4-methoxyphenyl)-1H-benzimidazol-6-yl]oxy]hexanoic acid methyl ester

https://huagongshe.com/reaction/1393592

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chlorobenzenesulfonyl chlorideHCID 7398—
Reactant6-[(5-Amino-1-(4-methoxyphenyl)-2-(4-methoxyphenyl)-1H-benzimidazol-6-yl)oxy]hexanoic acid methyl esterHCID 67365037—
Product6-[[5-[[(4-Chlorophenyl)sulfonyl]amino]-1-(4-methoxyphenyl)-2-(4-methoxyphenyl)-1H-benzimidazol-6-yl]oxy]hexanoic acid methyl esterHCID 11995867—

Reaction Steps

6-[(5-Amino-1-(4-methoxyphenyl)-2-(4-methoxyphenyl)-1H-benzimidazol-6-yl)oxy]hexanoic acid methyl ester was reacted with 4-chlorobenzenesulfonic acid chloride according to general operating instructions 13.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07345075B2
Source datasetuspto-grants-2008_03
ORD IDord-f0a8a78bb35046c7af1da3da8fb83788
Source noteuspto-grants-2008_03