3-Cyanopyridine → Nicotinamide

Participants

Reaction Conditions

Reaction Steps

0.096 mole 3-cyanopyridine was dissolved in 4.55 mole of water and 0.0115 mole of MnO2 prepared by above method was added to this. The mixture was refluxed at 100° C. for 13.5 hrs. The reaction mixture as cooled and filtered. The filtrate was evaporated to dryness to get solid nicotinamide 0.0879 mole. Yield of nicotinamide was 91.56 mole %.

Provenance & Evidence