HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → HCID 45080717, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | AZETIDINE-2-CARBOXAMIDE | HCID 14751894 | — |
| Product | HCID 45080717 | HCID 45080717 | 44% |
Reaction Steps
In a similar procedure as employed in the Intermediate Example 1, the azetidine-2-carboxylic acid amide (161 mg) obtained above was reacted with chloroacetyl chloride (200 mg) and then subjected to dehydration reaction to give the title compound (112 mg, Y.:44%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07345180B2 |
| Source dataset | uspto-grants-2008_03 |
| ORD ID | ord-d47eb158b0e947ca87ffc9ebf6273010 |
| Source note | uspto-grants-2008_03 |