HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23091904, compound → 1-(2,2-Dimethylpropionyl)-1H-indole-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23091904 | HCID 23091904 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(2,2-Dimethylpropionyl)-1H-indole-5-carboxylic acid | HCID 23091950 | 87% |
Reaction Steps
The benzyl 1-(2,2-dimethylpropionyl)-1H-indole-5-carboxylate (220 mg) obtained above was dissolved in ethanol, and 5% palladium on carbon (44 mg) was added thereto and stirred overnight at room temperature in a hydrogen atmosphere. Insoluble matter was removed by filtration, and the filtrate was concentrated under reduced pressure to give the title compound (140 mg, Y.:86%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07345180B2 |
| Source dataset | uspto-grants-2008_03 |
| ORD ID | ord-fc52fc0792604ff2b7098bed61d5828b |
| Source note | uspto-grants-2008_03 |