4-Methoxybenzenesulfonyl chloride → HCID 69307067, compound

HRID 1393873Notes

Reaction equation

HRID 1393873 reaction equation
[CH2:1]([O:3][C:4](=[O:14])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[C:8]([NH2:13])[CH:7]=1)[CH3:2].[CH3:15][O:16][C:17]1[CH:22]=[CH:21][C:20]([S:23](Cl)(=[O:25])=[O:24])=[CH:19][CH:18]=1.C(N(CC)CC)C>C(Cl)(Cl)Cl>[OH:12][C:9]1[CH:10]=[CH:11][C:6]([CH2:5][C:4]([O:3][CH2:1][CH3:2])=[O:14])=[CH:7][C:8]=1[NH:13][S:23]([C:20]1[CH:19]=[CH:18][C:17]([O:16][CH3:15])=[CH:22][CH:21]=1)(=[O:25])=[O:24]

Participants

5

Reactant 3

HCID 74014-Methoxybenzenesulfonyl chlorideHCID 8471TriethylamineHCID 13249301HCID 13249301, compound

Product 1

HCID 69307067HCID 69307067, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Ethyl(3-amino-4-hydroxyphenyl)acetate is reacted with 4-methoxybenzene sulfonyl chloride in chloroform in the presence of triethylamine, to give ethyl 2-[4-hydroxy-3-[[(4-methoxyphenyl)sulfonyl]amino]phenyl]acetate.

Sources & evidence

ORD record
ord-d667e3e6126045f99b2e619e75f2179b
Source dataset
uspto-grants-2008_03
Patent number
US07348017B2

Reaction notes

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