HCID 13839927, compound → HCID 16109184, compound

HRID 1393969Notes

Reaction equation

HRID 1393969 reaction equation
[CH3:1][C:2]([O:9][C:10]1[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][CH:11]=1)([CH3:8])[C:3]([O:5][CH2:6][CH3:7])=[O:4]>CO.[Pd]>[CH2:6]([O:5][C:3](=[O:4])[C:2]([CH3:8])([O:9][C:10]1[CH:11]=[CH:12][C:13]([NH2:16])=[CH:14][CH:15]=1)[CH3:1])[CH3:7]

Participants

4

Reactant 1

HCID 13839927HCID 13839927, compound

Product 1

HCID 16109184HCID 16109184, compoundYield 68%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

The title compound (1.2 g, 68%) was prepared from ethyl 2-methyl-2-(4-nitrophenyloxy)propanoate (2 g, 7.9 mmol) by hydrogenation with 10% Pd/C (1 g) in methanol at 50 psi and room temperature for 2 h.

Sources & evidence

ORD record
ord-811ce096333a446d89af0110909a2d28
Source dataset
uspto-grants-2008_03
Patent number
US07348334B2

Reaction notes

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