反应详情

The product from Example 2 Step (a) (2 g) was dissolved in dioxan (100 ml) and 6N HCl (100 ml) added. After 18 hrs at room temperature the solvent was evaporated and the resultant solid basified with NaOH (2M) to pH 11. The aqueous was extracted with ethyl acetate, the organic phase separated, dried, filtered and evaporated to leave the sub-title compound as an oil (1.1 g).

1. customAfter 18 hrs at room temperature the solvent was evaporated
2. extractionThe aqueous was extracted with ethyl acetate
3. customthe organic phase separated
4. customdried
5. filtrationfiltered
6. customevaporated