4-Piperidinol, 1-methyl- → HCID 59681791, compound
Reaction equation
[NH2:1][C:2]1[C:3]([C:7]2[N:8]([C:16]3[CH:17]=[C:18]([OH:22])[CH:19]=[CH:20][CH:21]=3)[C:9]3[CH:14]=[CH:13][N:12]=[CH:11][C:10]=3[N:15]=2)=[N:4][O:5][N:6]=1.[CH3:23][N:24]1[CH2:29][CH2:28][CH:27](O)[CH2:26][CH2:25]1>>[CH3:23][N:24]1[CH2:29][CH2:28][CH:27]([O:22][C:18]2[CH:17]=[C:16]([N:8]3[C:9]4[CH:14]=[CH:13][N:12]=[CH:11][C:10]=4[N:15]=[C:7]3[C:3]3[C:2]([NH2:1])=[N:6][O:5][N:4]=3)[CH:21]=[CH:20][CH:19]=2)[CH2:26][CH2:25]1Participants
3
Procedure
The title compound was prepared from the product of Example 39 using the general method of Example 50 using N-methyl-4-hydroxy-piperidine. MS (ES+) m/e 392 [M+H]+.
Sources & evidence
- ORD record
- ord-18f4c72294e24142bb03693637f7e848
- Source dataset
- uspto-grants-2008_03
- Patent number
- US07348339B2
Reaction notes
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