反应详情

The product of Step 1 (7.5 g, 26.01 mmol), was dissolved in ethanol (125 ml), and treated with 5 wt % Platinum on charcoal (750 mg), and stirred under 1 atm of H2 for 4 days. The reaction was filtered and the filtrate evaporated in vacuo. The residue was purified by silica gel chromatography eluting with a mixture of ether/dichloromethane (5:95) to afford the title compound (4.2 g, 62%); MS (ES+) m/e 263 [M+H]+.

1. filtrationThe reaction was filtered
2. customthe filtrate evaporated in vacuo
3. customThe residue was purified by silica gel chromatography
4. washeluting with a mixture of ether/dichloromethane (5:95)