Lithium hydroxide, monohydrate → HCID 85129031, compound

HRID 1394530Notes

Reaction equation

HRID 1394530 reaction equation
[CH3:1][C:2]1([CH3:29])[C:11]2[CH:10]=[C:9]([Se:12][C:13]#[C:14][C:15]([CH3:21])=[CH:16][C:17]([O:19]C)=[O:18])[CH:8]=[CH:7][C:6]=2[C:5]([C:22]2[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][CH:23]=2)=[CH:4][CH2:3]1.O.[OH-].[Li+]>>[CH3:1][C:2]1([CH3:29])[C:11]2[CH:10]=[C:9]([Se:12][C:13]#[C:14][C:15]([CH3:21])=[CH:16][C:17]([OH:19])=[O:18])[CH:8]=[CH:7][C:6]=2[C:5]([C:22]2[CH:27]=[CH:26][C:25]([CH3:28])=[CH:24][CH:23]=2)=[CH:4][CH2:3]1

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 86601142HCID 86601142, compound

Product 1

HCID 85129031HCID 85129031, compound

Procedure

In a manner similar to that of Example 1g, by reacting 0.23 g (0.5 mmol) of methyl 5-(8,8-dimethyl-5-p-tolyl-7,8-dihydro-2-naphthylselanyl)-3-methylpent-2-en4-ynoate with 0.23 g (5.5 mmol) of lithium hydroxide monohydrate, a pale yellow solid is obtained (0.05 g; yield=23%; m.p.=166° C.).

Workup

  1. customa pale yellow solid is obtained (0.05 g; yield=23%; m.p.=166° C.)

Sources & evidence

ORD record
ord-f7a67c19fa1b4bf98e2efcc5f85ba482
Source dataset
uspto-grants-2008_03
Patent number
US07348449B2

Reaction notes

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