Lithium hydroxide, monohydrate → HCID 73086782, compound

HRID 1394532Notes

Reaction equation

HRID 1394532 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[C:12]3[CH:13]=[CH:14][C:15]([Se:23][C:24]#[C:25][C:26]([CH3:32])=[CH:27][C:28]([O:30]C)=[O:29])=[CH:16][C:17]=3[C:18]([CH3:22])([CH3:21])[CH2:19][CH:20]=2)=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].O.[OH-].[Li+]>>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([C:11]2[C:12]3[CH:13]=[CH:14][C:15]([Se:23][C:24]#[C:25][C:26]([CH3:32])=[CH:27][C:28]([OH:30])=[O:29])=[CH:16][C:17]=3[C:18]([CH3:22])([CH3:21])[CH2:19][CH:20]=2)=[CH:9][CH:10]=1)([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 168937Lithium hydroxide, monohydrateHCID 86601144HCID 86601144, compound

Product 1

HCID 73086782HCID 73086782, compound

Procedure

In a manner similar to that of Example 3d, by reacting 0.19 g (0.37 mmol) of methyl 5-[5-(4-tert-butylphenyl)-8,8-dimethyl-7,8-dihydro-2-naphthylselanyl]-3-methylpent-2-en-4-ynoate with 0.19 g (4.5 mmol) of lithium hydroxide monohydrate, a cream-colored powder is obtained (0.06 g; yield=33%; m.p.=231° C.).

Workup

  1. customa cream-colored powder is obtained (0.06 g; yield=33%; m.p.=231° C.)

Sources & evidence

ORD record
ord-7eb9afefb99b43689c75ce3fa07817ab
Source dataset
uspto-grants-2008_03
Patent number
US07348449B2

Reaction notes

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