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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1394654Generated: November 2, 2026

Methyl morpholine oxide → 3-(2-Ethoxy-3,5-diisopropyl-phenyl)-imidazo[1,2-a]pyridine-6-carbaldehyde

https://huagongshe.com/reaction/1394654

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl morpholine oxideHCID 82029—
ReactantHCID 59682036HCID 59682036—
CatalystHCID 178419074HCID 178419074—
SolventDichloromethaneHCID 6344—
Product3-(2-Ethoxy-3,5-diisopropyl-phenyl)-imidazo[1,2-a]pyridine-6-carbaldehydeHCID 17952724—

Reaction Steps

Tetrapropylammonium perruthenate (24 mg, 0.07 mmol) and 4-methylmorpholine N-oxide (239.3 mg, 2.04 mmol) were added to a solution of [3-(2-ethoxy-3,5-diisopropyl-phenyl)-imidazo[1,2-a]pyridin-6-yl]-methanol (480 mg, 1.36 mmol) in dichloromethane under an atmosphere of nitrogen. After 3 h, the reaction was filtered through celite and evaporated. The residue used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07348359B2
Source datasetuspto-grants-2008_03
ORD IDord-408273f4821a4c6ca80161009035dabb
Source noteuspto-grants-2008_03