Phosphoric Acid → Quinoline-4-carboxylic acid (alpha-methyl-delta-diethylaminobutyl)amide diphosphate
Reaction equation
[CH3:1][CH:2]([NH:11][C:12]([C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[N:17]=[CH:16][CH:15]=1)=[O:13])[CH2:3][CH2:4][CH2:5][N:6]([CH2:9][CH3:10])[CH2:7][CH3:8].[P:24](=[O:28])([OH:27])([OH:26])[OH:25]>>[OH:28][P:24]([O:27][P:24]([OH:27])([OH:26])=[O:25])(=[O:26])[OH:25].[CH3:1][CH:2]([NH:11][C:12]([C:14]1[C:23]2[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=2)[N:17]=[CH:16][CH:15]=1)=[O:13])[CH2:3][CH2:4][CH2:5][N:6]([CH2:9][CH3:10])[CH2:7][CH3:8]Participants
3
Procedure
2-[4'-(5"-nitrofuryl-2")-1,3-butadienyl]quinoline-4-carboxylic acid (α-methyl-δ-diethylaminobutyl)amide diphosphate was prepared as described in Example 9 from 2-[2'-(5"-nitrofuryl-2")vinyl]quinoline-4-carboxylic acid (α-methyl-δ-diethylaminobutyl)amide and ortho-phosphoric acid. The yield was 68.1%, m.p. 176°-178° C.
Sources & evidence
- ORD record
- ord-dd75330445c74dcab98750422aaea439
- Source dataset
- uspto-grants-1980_05
- Patent number
- US04201784
Reaction notes
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