HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-Butylamine → HCID 20341547, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-Butylamine | HCID 6385 | — |
| Reactant | {2,4-Dimethyl-6-[(oxiran-2-yl)methoxy]phenyl}(4-methylphenyl)methanone | HCID 20341515 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 20341547 | HCID 20341547 | — |
Reaction Steps
A mixture of 2-(2,3-epoxypropoxy)-4,4',6-trimethylbenzophenone (10 g.), t-butylamine (10 ml.) and dry methanol (50 ml.) was heated at reflux overnight. The mixture was evaporated in vacuo, and the residue was recrystallized from cyclohexane to give DL-1-t-butylamino-3-(3,5-dimethyl-2-p-toluoylphenoxy)-2-hydroxypropane (7 g.), m.p. 116°-118° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04201790 |
| Source dataset | uspto-grants-1980_05 |
| ORD ID | ord-ea2b4652679040d5b21b03dd8d85f9ba |
| Source note | uspto-grants-1980_05 |