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HRID1395065

反应详情

EQUATION

反应方程式

HRID 1395065 的结构方程式

REACTANTS

反应物

3
结构：CCCC(N)C(=O)O
HCID824

(+-)-Norvaline

C5H11NO2

结构：CC(C)C[C@H](N)C(=O)O
HCID6106

L-Leucine

C6H13NO2

结构：CCC1OC(=O)CC(OC(C)=O)C(C)C(OC2OC(C)C(OC3CC(C)(O)C(O)C(C)O3)C(N(C)C)C2O)C(CC=O)CC(C)C(=O)/C=C/C(C)=C/C1COC1OC(C)C(O)C(OC)C1OC
HCID6426606

3-Acetyltylosin

C48H79NO18

PRODUCTS

生成物

2
结构：CC(C)C[C@H](N)C(=O)O
HCID6106

L-Leucine

C6H13NO2

结构：CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@H](N(C)C)[C@H]2O)[C@@H](CC=O)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO[C@@H]1O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]1OC
HCID5280440

Tylosin

C46H77NO17

PROCEDURE

实验过程

A similar cultivation and reaction as in Example 1 was carried out by substituting L-leucine as the isovaleryl donor for DL-norvaline. From 60 g of tylosin and 15 g of L-leucine, about 900 mg of white crystals of 4"-isovaleryltylosin and 17 g of white crystals of 3-acetyltylosin were obtained.

WORKUP

后处理

  1. customA similar cultivation and reaction as in Example 1