Glycine → (2R)-2-(((tert-butoxy)carbonyl)amino)-3-methylbutanoic acid

HRID 1395103Notes

Reaction equation

HRID 1395103 reaction equation
NC[C:3]([OH:5])=[O:4].N[C@H](C(O)=O)C.[NH2:12][C@H:13]([C:17]([OH:19])=[O:18])[CH:14]([CH3:16])[CH3:15].N[C@H](C(O)=O)[CH2:22][C:23]1[CH:28]=CC=C[CH:24]=1.N[C@H](C(O)=O)CCCCN>>[C:23]([O:5][C:3]([NH:12][C@@H:13]([C:17]([OH:19])=[O:18])[CH:14]([CH3:16])[CH3:15])=[O:4])([CH3:28])([CH3:24])[CH3:22]

Participants

6

Reactant 5

HCID 750GlycineHCID 5950L-AlanineHCID 5962L-LysineHCID 6140L-PhenylalanineHCID 6287L-Valine

Product 1

HCID 637605(2R)-2-(((tert-butoxy)carbonyl)amino)-3-methylbutanoic acid

Procedure

2Thr, 2.12; Ser, 1.09; Gly, 0.95; Ala, 1.13; Val, 0.98; 3 Phe, 3.09; 2 Lys, 2.00.

Sources & evidence

ORD record
ord-0e151772a6884a8ca61dbfbe839f7acd
Source dataset
uspto-grants-1980_05
Patent number
US04202802

Reaction notes

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