Diazomethane → HCID 54488354, compound

HRID 1395131Notes

Reaction equation

HRID 1395131 reaction equation
[Cl:1][C:2]1[CH:18]=[CH:17][C:5]([CH2:6][NH:7][C:8]([S:10][CH2:11][CH2:12][CH2:13][C:14]([OH:16])=[O:15])=[S:9])=[CH:4][CH:3]=1.[N+](=[CH2:21])=[N-]>C(OCC)C>[CH3:21][O:15][C:14](=[O:16])[CH2:13][CH2:12][CH2:11][S:10][C:8](=[S:9])[NH:7][CH2:6][C:5]1[CH:17]=[CH:18][C:2]([Cl:1])=[CH:3][CH:4]=1

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 203402724-({[(4-Chlorophenyl)methyl]carbamothioyl}sulfanyl)butanoic acid

Product 1

HCID 54488354HCID 54488354, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

1.5 G. of 4-{[(p-chlorobenzyl)thiocarbamoyl]thio}-butyric acid were dissolved in 30 ml. of diethyl ether and treated with an excess of an ethereal diazomethane solution. The resulting solution was evaporated. The residue was recrystallized from cyclohexane, and 1.2 g. of 4-{[(p-chlorobenzyl)thiocarbamoyl]thio}-butyric acid methyl ester having a melting point of 60°-62° C. were obtained.

Workup

  1. customThe resulting solution was evaporated
  2. customThe residue was recrystallized from cyclohexane, and 1.2 g

Sources & evidence

ORD record
ord-eff9508acb444f87b1c47e2088508cdd
Source dataset
uspto-grants-1980_05
Patent number
US04202832

Reaction notes

Loading…