1-(2-Methoxyphenyl)piperazine → HCID 20340748, compound

Participants

Reaction Steps

A solution of 3.9 g of 2-(3-chloropropyl)-s-triazolo[1,5-a]pyridine, 3.8 g of 1-o-methoxyphenylpiperazine and 2.8 g of potassium carbonate in 150 ml of dimethylformamide was refluxed for 8 hours. Then the reaction mixture was proceeded by the same manner as described in Example 2. The compound was recrystallized from cyclohexane to give colorless prisms, mp 55°-55.5° C. Yield was 60%. Anal. Calcd. for C20H25ON5 : C, 68.35; H, 7.17; N, 19.53. Found: C, 68.20; H, 6.94; N, 20.21.

Provenance & Evidence