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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1395377Generated: November 1, 2026

5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine → 1-Nitro-2-(2-propynylamino)-2-{2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethylamino}ethylene

https://huagongshe.com/reaction/1395377

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamineHCID 162203—
ReactantN-[1-(Methylsulfanyl)-2-nitroethenyl]prop-2-yn-1-amineHCID 71401969—
Product1-Nitro-2-(2-propynylamino)-2-{2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethylamino}ethyleneHCID 173413—

Reaction Steps

A solution of the product of Step A is reacted with about an equimolar amount of 2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethylamine to give, after workup and chromatography as in Example 1, the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04203909
Source datasetuspto-grants-1980_05
ORD IDord-6e1a511ec2244b6a9ff82b25ab018e30
Source noteuspto-grants-1980_05