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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1395379Generated: November 2, 2026

5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine → N-Cyano-N'-(2-propyn-1-yl)-N"-{2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethyl}guanidine

https://huagongshe.com/reaction/1395379

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamineHCID 162203—
ReactantCarbamimidothioic acid, N-cyano-N'-2-propynyl-, methyl esterHCID 2805748—
ProductN-Cyano-N'-(2-propyn-1-yl)-N"-{2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethyl}guanidineHCID 136088352—

Reaction Steps

The product of Step A is reacted with about an equimolar amount of 2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethylamine in a non-reactive solvent to give, after workup and chromatography as in Example 3, the title product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04203909
Source datasetuspto-grants-1980_05
ORD IDord-94d2b60317074c9191de57358d65310e
Source noteuspto-grants-1980_05