HCID 20339444, compound → HCID 20339636, compound

Participants

Reaction Steps

A solution of N-(2-acetoxyethyl)-N'-(2-dimethylamino ethyl)-N'-(4,6-dimethyl-2-pyridyl)urea (11.5 g, 0.034 mole) in 1:1 ethanol-aqueous ammonia (300 ml.) is allowed to overnight at room temperature. The solvent is then removed under vacuum and the residue is crystallized from acetonitrile. The yield of crude product is 7.30 g, m.p. 173-176. Recrystallization from acetonitrile gives pure product melitng at 177°-179° C.

Provenance & Evidence