Methyl iodide → HCID 20337886, compound

HRID 1395654Notes

Reaction equation

HRID 1395654 reaction equation
[C:1]1([C:7]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[C:8]2[CH2:17][N:16]3[CH:11]([CH2:12][CH2:13][CH2:14][CH2:15]3)[CH2:10][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:24][I:25]>CO>[CH3:24][I:25].[C:1]1([C:7]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[C:8]2[CH2:17][N:16]3[CH:11]([CH2:12][CH2:13][CH2:14][CH2:15]3)[CH2:10][CH2:9]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 12519354HCID 12519354, compound

Product 1

HCID 20337886HCID 20337886, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 30 ml. of methanol was dissolved 2.0 g. of 3-diphenylmethylenequinolizidine. After adding 1.5 ml. of methyl iodide to the solution, the mixture was stirred at room temperature for 24 hrs. After completion of the reaction, the solvent was distilled off and the resulting crystals were recrystallized from acetone to obtain 1.6 g. of colorless prisms showing a melting point of 221° to 224° C.

Workup

  1. additionAfter adding 1.5 ml
  2. customAfter completion of the reaction
  3. distillationthe solvent was distilled off
  4. customthe resulting crystals were recrystallized from acetone
  5. customto obtain 1.6 g

Sources & evidence

ORD record
ord-be75366381874ec7a49f0bb9e176b85e
Source dataset
uspto-grants-1980_05
Patent number
US04205074

Reaction notes

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