HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 20574340, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Chloro-N,N-dimethylethylamine | HCID 7901 | — |
| Reactant | HCID 20574342 | HCID 20574342 | — |
| Reactant | HCID 20574349 | HCID 20574349 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 20574340 | HCID 20574340 | — |
Reaction Steps
In a manner analogous to that described in Example 1, 30.6 g. 1-allyl-3-hydroxy-4-phenyl-3-pyrrolin-2-one are reacted with 23.0 g. β-dimethylaminoethyl chloride. The base obtained is reacted with gaseous hydrogen chloride in ethyl acetate. There is obtained 15.0 g. (45.5% of theory) 1-allyl-3-(β-dimethylaminoethoxy)-4-phenyl-3-pyrrolin-2-one hydrochloride; m.p. 115°-117° C., after recrystallization from methyl ethyl ketone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04205078 |
| Source dataset | uspto-grants-1980_05 |
| ORD ID | ord-4ebe428a9af74464b1b37fa330bc2310 |
| Source note | uspto-grants-1980_05 |