HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycolic Acid → HCID 12939690, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycolic Acid | HCID 757 | — |
| Reactant | 7-Amino-4-methylcoumarin | HCID 92249 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 12939690 | HCID 12939690 | — |
Reaction Steps
8.7 g of 7-amino-4-methyl-coumarin are stirred, under nitrogen, in a round-bottomed flask, together with 7.6 g of glycollic acid at an oil bath temperature of 150°-160°. The reaction mass becomes crystalline after about 30 minutes. It is diluted with water and the product is filtered off with suction and recrystallised from 200 ml of dimethylformamide and 100 ml of ethanol. 7-Hydroxyacetamido-4-methyl-coumarin with a melting point of 253°-254° is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04205082 |
| Source dataset | uspto-grants-1980_05 |
| ORD ID | ord-4437a395496846aaa58f48208b4c1de1 |
| Source note | uspto-grants-1980_05 |