N-Acetyl-DL-methionine → L-Methionine

HRID 1395699Notes

Reaction equation

HRID 1395699 reaction equation
C([NH:4][CH:5]([C:10]([OH:12])=[O:11])[CH2:6][CH2:7][S:8][CH3:9])(=O)C>O>[NH2:4][C@H:5]([C:10]([OH:12])=[O:11])[CH2:6][CH2:7][S:8][CH3:9]

Participants

3

Reactant 1

HCID 6180N-Acetyl-DL-methionine

Product 1

HCID 6137L-Methionine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

100 g of the above catalyst was swelled in water for about one hour and packed into a jacketed glass column having 2.5 cm diameter and 80 cm height and kept at 50° C. Solution of N-acetyl-DL-methionine (0.2 mol, pH 7.0, added with 5.0×10-4 mol CoCl2) was continuously flown down from the top of the column at a flow rate of 1000 ml/hr. The reaction solution flown out of the bottom of the column was sampled on every certain interval of time and the amount of the L-methionine produced was determined by way of ninhydrine colorimetry. The results are shown in table 6.

Workup

  1. customkept at 50° C
  2. aliquotwas sampled on every certain interval of time

Sources & evidence

ORD record
ord-3890561da99a43de8dfc1b07f0cfc902
Source dataset
uspto-grants-1980_05
Patent number
US04205128

Reaction notes

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