反应详情

1-(p-Methoxyphenyl)-4-(2-hydroxyethyl)piperazine (10 g) was refluxed 20 hours with 100 ml 48% HBr and concentrated as far as possible on the rotovap. The mixture was filtered and washed with acetone to give a solid which was recrystallized from alcohol to give the product.

1. concentrationconcentrated as far as possible on the rotovap
2. filtrationThe mixture was filtered
3. washwashed with acetone
4. customto give a solid which
5. customwas recrystallized from alcohol
6. customto give the product