HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131732103, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 66974052 | HCID 66974052 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 131732103 | HCID 131732103 | — |
Reaction Steps
To a solution consisting of 3-(2,2-difluoro-benzo[1,3]dioxol-5-ylmethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester (1.36 g, 3.98 mmol) and dichloromethane (20 mL) was added HCl (4 M solution in dioxane, 6 mL). The reaction mixture was stirred at rt for 18 h. The resultant mixture was concentrated to give the title compound in quantitative yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901111B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-f4bd942d89134a7f9edaf912f71978b9 |
| Source note | uspto-grants-2014_12 |