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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1396028Generated: November 3, 2026

Hydrochloric Acid → HCID 131732103, compound

https://huagongshe.com/reaction/1396028

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 66974052HCID 66974052—
SolventDichloromethaneHCID 6344—
ProductHCID 131732103HCID 131732103—

Reaction Steps

To a solution consisting of 3-(2,2-difluoro-benzo[1,3]dioxol-5-ylmethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester (1.36 g, 3.98 mmol) and dichloromethane (20 mL) was added HCl (4 M solution in dioxane, 6 mL). The reaction mixture was stirred at rt for 18 h. The resultant mixture was concentrated to give the title compound in quantitative yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901111B2
Source datasetuspto-grants-2014_12
ORD IDord-f4bd942d89134a7f9edaf912f71978b9
Source noteuspto-grants-2014_12