Ammonia → HCID 86689739, compound

Participants

Reaction Steps

6-Chloro-4-(6-ethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid ethyl ester (241 mg, 0.786 mmol) was suspended in 7M ammonia in methanol (9 mL). After 3 h, the reaction mixture was concentrated in vacuo to give 6-chloro-4-(6-ethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide (218 mg, 100%) as an off-white solid which was used directly in the next step without purification. LCMS (EI/CI) m/z: 278 [M+H].

Provenance & Evidence