HCID 68023818, compound → HCID 86710220, compound

Participants

Reaction Steps

Tert-butyl [5-(4-chloro-2-trifluoromethyl-phenylamino)-3-fluoro-pyridin-2-ylmethyl]-carbamate (50 mg, 0.12 mmol) was stirred for 2 hours at 60° C. in a mixture of 2 mL of semi-concentrated hydrochloric acid and 3 mL of dioxane. This was then concentrated to dryness, the residue was stirred with 3 mL of toluene and evaporated down once more. The product was thus obtained in a yield of 84% of theory.

Provenance & Evidence